Leveraging Siglec glycoimmune checkpoints to boost CAR therapy efficacy
The International E. Balzan Prize Foundation
Arkaitz Carracedo
Cancer Cell Signaling & Metabolism Lab
Coordinator:
The regulation of polyamine homeostasis in cancer.
Europe
ERC Proof of Concept
Jesús Jímenez-Barbero
Chemical Glycobiology Lab
Coordinator:
BiParatopic – Bispecific bi-paratopic antibodies for the treatment of cancer
ERC Synergy Grant
Raúl Pérez-Jiménez
Synthetic Biology
Lab
Coordinator:
RGNcestry – Tracing and harnessing the ancestry of RNA-guided nucleases
MSCA Doctoral Networks
Juan Anguita
Inflammation and Macrophage Plasticity Lab
Coordinator:
EVADERE – Enhaced VAccines DEsign against antimicrobial Resistance
Private
IX Research Project: For a world without ALS
Raúl Pérez-Jiménez
Synthetic Biology
Lab
Synthetic CRISPR systems and base editing for high-precision, unrestricted correction of ALS-associated mutations
IV Research Projects: For a World Without ALS - Young Researchers
Ylenia Jabalera
Synthetic Biology
Lab
New LNP-based database editor systems for the study and correction of ALS-associated mutations
XXII National Competition for Research Grants in Life and Material Sciences
June Ereño-Orbea
Cancer Glycoimmunology Lab
Boosting CAR therapy efficacy with modified glycans
CaixaResearch Health 2025
June Ereño-Orbea
Cancer Glycoimmunology Lab
GlycoTARGET – Advanced platform for targeting tumor-associated glycans
“Sinergias” AECC
Gabriel Ortega
Precision Medicine and Metabolism Lab
SMARTherapy – antibody-based Sensor for Monitoring Adverse Reactions in immunotherapy
Spain
Knowledge Generation Projects
9 funded projects
4 associated predoctoral contracts
2.484.000 €
536.800 €
91% Success rate
Proof of Concept Projects
4 funded projects
898.183 €
50% Success rate
Public-Private Partnership Projects
Coordinator:
ERYSAFETY – In vivo research on hemolytic anemia for drug safety assessment
Juan Manuel Falcón
Exosomes Lab
Urko M. Marigorta
Integrative Genomics Lab
Ana Ruiz- Sáenz
Cancer Therapy Resistance Lab
Coordinator:
CATIB – Novel CCR9 antibody for the treatment of inflammatory bowel disease
Basque Country
ELKARTEK
Collaborative Fundamental Research Project
1.248.658 €
DESARROLLO DE MODELOS DE MEDICINA PERSONALIZADA PARA LA PREDICCIÓN TEMPRANA DE ENFERMEDADES PREVALENTES E INFECCIOSAS
Leader:
Cancer Research Projects
Marco Piva
Cancer Cell Signaling and Metabolism Lab
Advanced Therapies for Metastatic Prostate Cancer: Bispecific Antibodies and Nanotechnology
Basic and Applied Research Projects
Isabel Mendizabal
Precision Cancer Multiomics Lab
Unraveling prostate progression: Longitudinal analysis and spatial transcriptomics to identify key biomarkers and mechanisms in the transition from hyperplasia to cancer
IKUR Challenges: Neurobioscience
NeuCRISPR – Development of broad action CRISPR gene editors for Amyotrophic Lateral Sclerosis (ALS)
Raúl Pérez-Jiménez
Synthetic Biology
Lab
Juan Manuel Falcón
Exosomes Lab
ExoPsyCog II – Brain-derived plasma extracellular vesicles as biomarkers and treatment of psychotic disorders